How inflammation and hypoxia damage the brain

A new study shows that a combination of inflammation and hypoxia activates microglia in a way that persistently weakens the connection between neurons, contributing to brain damage in conditions such as stroke and Alzheimer's disease.

http://www.eurekalert.org/pub_releases/2014-03/uobc-scb031214.php

[3625] Zhang, J., Malik A., Choi H. B., Ko R. W. Y., Dissing-Olesen L., & MacVicar B. A.
(2014).  Microglial CR3 Activation Triggers Long-Term Synaptic Depression in the Hippocampus via NADPH Oxidase.
Neuron. 82(1), 195 - 207.

Related News

The study involved 74 non-smokers with amnestic

More data from the long-running Mayo Clinic Study of Aging has revealed that, in this one part of the U.S.

We know that physical exercise greatly helps you prevent cognitive decline with aging. We know that mental stimulation also helps you prevent age-related cognitive decline. So it was only a matter of time before someone came up with a way of combining the two.

The age at which cognitive decline begins has been the subject of much debate. The Seattle longitudinal study has provided most of the evidence that it doesn’t begin until age 60.

The study involved 104 healthy older adults (average age 87) participating in the Oregon Brain Aging Study.

Growing evidence points to greater education and mentally stimulating occupations and activities providing a

A study involving 159 older adults (average age 76) has confirmed that the amount of brain tissue in specific regions is a predictor of Alzheimer’s disease development.

The olfactory bulb is in the oldest part of our brain. It connects directly to the

Why is diabetes associated with cognitive impairment and even dementia in older adults? New research pinpoints two molecules that trigger a cascade of events that end in poor blood flow and brain atrophy.

Iron deficiency is the world's single most common nutrient deficiency, and a well-known cause of impaired cognitive, language, and motor development. Many countries therefore routinely supplement infant foods with iron.

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news