Alzheimer's a much larger cause of death than reported

A new U.S. study suggests that Alzheimer's disease and other dementias are markedly under-reported on death certificates and medical records. Death certificates tend to only provide an immediate cause, such as pneumonia, and don’t mention the underlying condition that provoked it.

The study involved 2,566 older adults (65+; mean age 78) who received annual testing for dementia. The death rate was more than four times higher for those aged 75-84 who had been diagnosed with Alzheimer’s, and nearly three times higher in those with Alzheimer’s aged 85+. More than one-third of all deaths in those age groups were attributable to Alzheimer's disease. Median time from Alzheimer’s diagnosis to death was 3.8 years.

All this translates into an estimated mortality rate from Alzheimer's that is five to six times higher than the accepted number (derived from death certificates), which has put Alzheimer’s as the 6th leading cause of death.

http://www.eurekalert.org/pub_releases/2014-03/aaon-sad022614.php

[3579] James, B. D., Leurgans S. E., Hebert L. E., Scherr P. A., Yaffe K., & Bennett D. A.
(2014).  Contribution of Alzheimer disease to mortality in the United States.
Neurology. 82(12), 1045 - 1050.

Related News

Here’s a different aspect to

More findings from the long-running Mayo Clinic Study of Aging reveal that using a computer plus taking moderate exercise reduces your risk of mild cognitive impairment significantly more than you would expect from simply adding together these two beneficial activities.

The study involved 4,134 people (average age 59) who worked at the French national gas and electric company, of whom most worked at the company for their entire career.

I’ve mentioned before that, for some few people, exercise doesn’t seem to have a benefit, and the benefits of exercise for fighting age-related cognitive decline may not apply to those carrying the Alzheimer’s gene.

Data from the Women's Health Study, involving 6,183 older women (65+), has found that it isn’t the amount of fat but the type of fat that is associated with cognitive decline.

Interpreting brain activity is a very tricky business. Even the most basic difference can be interpreted in two ways — i.e., what does it mean if a region is more active in one group of people compared to another?

Damage to the retina (retinopathy) doesn’t produce noticeable symptoms in the early stages, but a new study indicates it may be a symptom of more widespread damage. In the ten-year study, involving 511 older women (average age 69), 7.6% (39) were found to have retinopathy.

Older adults who sleep poorly react to stress with increased inflammation

Data from the very large and long-running Cognitive Function and Ageing Study, a U.K. study involving 13,004 older adults (65+), from which 329 brains are now available for analysis, has found that cognitive lifestyle score (CLS) had no effect on Alzheimer’s pathology.

Previous research has been equivocal about whether cognitive training helps cognitively healthy older adults.

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news