Alzheimer's a much larger cause of death than reported

A new U.S. study suggests that Alzheimer's disease and other dementias are markedly under-reported on death certificates and medical records. Death certificates tend to only provide an immediate cause, such as pneumonia, and don’t mention the underlying condition that provoked it.

The study involved 2,566 older adults (65+; mean age 78) who received annual testing for dementia. The death rate was more than four times higher for those aged 75-84 who had been diagnosed with Alzheimer’s, and nearly three times higher in those with Alzheimer’s aged 85+. More than one-third of all deaths in those age groups were attributable to Alzheimer's disease. Median time from Alzheimer’s diagnosis to death was 3.8 years.

All this translates into an estimated mortality rate from Alzheimer's that is five to six times higher than the accepted number (derived from death certificates), which has put Alzheimer’s as the 6th leading cause of death.

http://www.eurekalert.org/pub_releases/2014-03/aaon-sad022614.php

[3579] James, B. D., Leurgans S. E., Hebert L. E., Scherr P. A., Yaffe K., & Bennett D. A.
(2014).  Contribution of Alzheimer disease to mortality in the United States.
Neurology. 82(12), 1045 - 1050.

Related News

Tau protein stabilizes structures that transport supplies from the center of the cell to the extremities, but sometimes some tau is not bound to these microtubules and instead clumps together into

A study involving genetically engineered fruit flies adds to our understanding of why sleep and bioclock disruptions are common in those with Alzheimer's disease.

A new study shows that a combination of inflammation and hypoxia activates microglia in a way that persistently weakens the connection between

A new function has been found for the

New research helps explain the role of amyloid-beta plaques in the development of Alzheimer's, by finding that the

Creating amyloid-beta requires the convergence of a protein called

A Swedish study of some 4,000 60-year-olds has found that regular “non-exercise” physical activity such as gardening or DIY significantly reduced risk of heart attack or stroke, with those who were most active on a daily basis having a 27% lower risk of a heart attack or stroke and a 30% reduced

A year-long study involving 424 sedentary, mobility-limited seniors aged 70-89, has found that variants in a specific gene (the ACE I/D gene) affect seniors’ ability to benefit from exercise.

Data from the American National Health and Nutrition Examination Survey (NHANES) III, involving 3,659 individuals (men aged 55+; women 65+), has found that the more muscle mass older adults have, the less likely they are to die prematurely.

A four-year study involving 1,502 healthy older adults (50+) has found that the frequency of negative interactions with family members (not partners or children) and friends was associated with an increased risk of developing hypertension in women (but not in men).

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news