Rigorous exercise does not slow dementia decline

  • A study involving nearly 500 people with dementia has found that a rigorous physical exercise program did nothing to slow their decline.

A number of studies have found that physical exercise can help delay the onset of dementia, however the ability of exercise to slow the decline once dementia has set in is a more equivocal question. A large new study answers this question in the negative.

The study involved 494 people with mild-to-moderate dementia (average age 77; 61% male), of whom 329 were randomly assigned to a four-month aerobic and strength exercise programme and 165 were assigned to usual care. The exercise program was personalized, and involved two 60-90 minute gym sessions every week, plus a further hour at home. Nearly two-thirds of the exercise group attended more than three-quarters of the gym sessions.

While the exercise group did get physically fitter, their cognitive fitness (as measured by ADAS-cog score) actually worsened slightly.

The researchers emphasize that this was a specialized and intense exercise program, and in no way should it be taken to mean that gentle exercise, which is good for dementia sufferers, should be avoided.

https://www.theguardian.com/society/2018/may/16/rigorous-exercise-makes-dementia-worse-study-concludes

Reference: 

Related News

Tau protein stabilizes structures that transport supplies from the center of the cell to the extremities, but sometimes some tau is not bound to these microtubules and instead clumps together into

A study involving genetically engineered fruit flies adds to our understanding of why sleep and bioclock disruptions are common in those with Alzheimer's disease.

A new study shows that a combination of inflammation and hypoxia activates microglia in a way that persistently weakens the connection between

A new function has been found for the

New research helps explain the role of amyloid-beta plaques in the development of Alzheimer's, by finding that the

Creating amyloid-beta requires the convergence of a protein called

A Swedish study of some 4,000 60-year-olds has found that regular “non-exercise” physical activity such as gardening or DIY significantly reduced risk of heart attack or stroke, with those who were most active on a daily basis having a 27% lower risk of a heart attack or stroke and a 30% reduced

A year-long study involving 424 sedentary, mobility-limited seniors aged 70-89, has found that variants in a specific gene (the ACE I/D gene) affect seniors’ ability to benefit from exercise.

Data from the American National Health and Nutrition Examination Survey (NHANES) III, involving 3,659 individuals (men aged 55+; women 65+), has found that the more muscle mass older adults have, the less likely they are to die prematurely.

A four-year study involving 1,502 healthy older adults (50+) has found that the frequency of negative interactions with family members (not partners or children) and friends was associated with an increased risk of developing hypertension in women (but not in men).

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news