Low vitamin D speeds age-related cognitive decline

  • On average, older adults with low levels of vitamin D showed much faster decline in episodic memory and executive function.
  • Older adults with dementia had significantly lower levels of vitamin D compared to those with MCI or normal cognition.
  • Low vitamin D was more common in African-Americans and Hispanics, compared to whites.

A study involving 382 older adults (average age 75) followed for around five years, has found that those who don’t get enough vitamin D may experience cognitive decline at a much faster rate than people who have adequate vitamin D.

Participants included 17.5% with dementia at the beginning of the study, 32.7% with MCI, and 49.5% cognitively healthy.

Those with dementia had lower levels of vitamin D than the other two groups.

While some people with low vitamin D didn’t show any cognitive decline and some with adequate vitamin D declined quickly, people with low vitamin D on average declined two to three times as fast as those with adequate vitamin D, in two crucial cognitive domains: episodic memory and executive function. Semantic memory and visuospatial ability were not significantly affected.

Factors such as age, gender, education, BMI, season of blood draw, vascular risk, and presence of the 'Alzheimer's gene', ApoE4, were controlled for.

Unlike previous studies of vitamin D and dementia, the participants were racially and ethnically diverse and included whites (41%), African Americans (30%), and Hispanics (25%). Nearly two-thirds (61%) had low vitamin D levels in their blood, including 54% of the whites and 70% of the African-Americans and Hispanics.

Vitamin D is primarily obtained through sun exposure. Accordingly, people with darker skin are more likely to have low levels of vitamin D because melanin blocks ultra-violet rays.

It remains to be seen whether Vitamin D supplements could slow cognitive decline.

http://www.futurity.org/vitamin-d-cognitive-decline-1003932/

 

Reference: 

Related News

There's quite a bit of evidence now that socializing — having frequent contact with others — helps protect against cognitive impairment in old age. We also know that depression is a risk factor for cognitive impairment and dementia.

Problems with myelin — demyelination (seen most dramatically in MS, but also in other forms of neurodegeneration, including normal

The

It’s been unclear whether hormone therapy helps older women reduce their risk of Alzheimer’s or in fact increases the risk.

In a large Mayo Clinic study, self-reported diet was found to be significantly associated with the risk of seniors developing mild cognitive impairment or dementia over a four-year period.

A study using data from the Lothian Birth Cohort (people born in Scotland in 1936) has analyzed brain scans of 638 participants when they were 73 years old.

Caffeine has been associated with a lower of developing Alzheimer's disease in some recent studies.

Green tea is thought to have wide-ranging health benefits, especially in the prevention of cardiovascular disease, inflammatory diseases, and diabetes.

I reported a few months ago on some evidence of a link between disturbed sleep and the development of Alzheimer’s. Now a mouse study adds to this evidence.

I’ve reported before on the growing evidence that metabolic syndrome in middle and old age is linked to greater risk of cognitive impairment in old age and faster decline.

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news