Over 90% of dementia cases in China are undetected

A survey of 7,072 older adults in six provinces across China, with one rural and one urban community in each province, has identified 359 older adults with dementia and 328 with depression. There were only 26 participants who had doctor-diagnosed dementia reported and 26 who had doctor-diagnosed depression. Overall, 93% of dementia cases and 93% of depression were not detected.

Undetected dementia was strongly associated with low socioeconomic status such as a low educational and occupational class, and living in a rural area.

In comparison, research in high income countries has found that about 60% of older adults with dementia are not diagnosed, and generally there has not been a strong association between low socioeconomic status and undetected dementia. One factor in China’s high rate may be that most older Chinese live with their families, who may be inclined to see dementia as a normal part of aging.

http://www.eurekalert.org/pub_releases/2013-07/kcl-o9072413.php

 

New estimates of dementia in China

A new review of 89 studies, involving more than 340,000 participants in total, has estimated that 9.19 million people in China had dementia in 2010, of whom 5.69 million had Alzheimer’s disease. Previous studies appear to have considerably underestimated the true burden of dementia in China, largely due to limited data availability. However, this study examined a much wider range of data sources than earlier studies, including many Chinese-language reports.

Of the 340 247 participants, 6357 had Alzheimer's disease (1.87%). Of 254,367 assessed for other forms of dementia, 3543 (1.4%) had vascular dementia, frontotemporal dementia, or Lewy body dementia.

Total dementia prevalence in 1990 was 1·8% at 65-69 years, and 42·1% at age 95-99 years; in 2010, prevalence had increased to 2·6% and 60·5%, respectively.

Prevalence was higher for women than men, but didn't differ significantly between urban and rural residents.

http://www.eurekalert.org/pub_releases/2013-06/l-mco060513.php

[3561] Chen, R., Hu Z., Chen R-L., Ma Y., Zhang D., & Wilson K.
(2013).  Determinants for undetected dementia and late-life depression.
The British Journal of Psychiatry. 203(3), 203 - 208.

[3559] Chan, K Y., Wang W., Wu J J., Liu L., Theodoratou E., Car J., et al.
(2013).  Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990–2010: a systematic review and analysis.
The Lancet. 381(9882), 2016 - 2023.

Related News

While everyone agrees that amyloid-beta protein is part of the problem, not everyone agrees that amyloid plaques are the cause (or one of them) of Alzheimer’s. Other forms of amyloid-beta have been pointed to, including floating clumps called oligomers or ADDLs.

A few months ago, I reported on an exciting finding that

The American Academy of Neurology has updated its guidelines on when people with dementia should stop driving.

Another gene has been identified that appears to increase risk of Alzheimer’s. The gene, MTHFD1L, is located on chromosome six.

Previous research has found that unexplained weight loss is an early sign of Alzheimer's.

Amnestic mild cognitive impairment often leads to Alzheimer's disease, but what predicts aMCI?

A pilot study involving 21 institutionalized individuals with moderate-to-severe Alzheimer’s found that, although drinking two 4-oz glasses of apple juice daily for a month produced no change in the Dementia Rating Scale or in the Activities of Daily Living measure, there was a significant (27%)

A pilot study involving 10 patients with moderate Alzheimer's disease, of whom half were randomly assigned to the treatment, has found that two weeks of receiving daily (25 minute) periods of repetitive transcranial magnetic stimulation to the prefrontal

A study involving outpatients with early stage Alzheimer’s found that their performance on some computerized tests of executive function and visual attention, including a simulated driving task, improved significantly after three months of taking

A study involving 54 older adults (66-76) and 58 younger adults (18-35) challenges the idea that age itself causes people to become more risk-averse and to make poorer decisions.

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news