Deep brain therapy effective in early Parkinson’s

03/2013

A 2-year trial involving 251 patients with Parkinson's disease and early motor complications (mean age, 52 years; mean duration of disease, 7.5 years) has found that those given deep brain stimulation surgery significantly improved their quality of life, motor disability, activities of daily living, levodopa-induced motor complications, and time with good mobility and no dyskinesia. Those given normal medical therapy, on the other hand, declined or at best got no worse. Serious adverse events related to surgical implantation or the neurostimulation device occurred in 18% of patients.

“The study has confirmed the best medical practice for a person with Parkinson’s disease is to perform DBS surgery around 4 to 7 years into the condition, as opposed to waiting until the medications stop working.”

http://www.futurity.org/health-medicine/deep-brain-therapy-effective-in-early-parkinsons/

[3321] Schuepbach, W. M. M., Rau J., Knudsen K., Volkmann J., Krack P., Timmermann L., et al.
(2013). Neurostimulation for Parkinson's Disease with Early Motor Complications.
New England Journal of Medicine. 368(7), 610 - 622.

seniors

Related News

Nicotine patch shows benefits in mild cognitive impairment

The study involved 74 non-smokers with amnestic

Higher risk of mild cognitive impairment among older men

More data from the long-running Mayo Clinic Study of Aging has revealed that, in this one part of the U.S.

'Exergames' may provide greater cognitive benefit for older adults

We know that physical exercise greatly helps you prevent cognitive decline with aging. We know that mental stimulation also helps you prevent age-related cognitive decline. So it was only a matter of time before someone came up with a way of combining the two.

Cognitive decline begins in middle age

The age at which cognitive decline begins has been the subject of much debate. The Seattle longitudinal study has provided most of the evidence that it doesn’t begin until age 60.

Diet linked to brain atrophy in old age

The study involved 104 healthy older adults (average age 87) participating in the Oregon Brain Aging Study.

Physical evidence bilingualism delays onset of Alzheimer's symptoms

Growing evidence points to greater education and mentally stimulating occupations and activities providing a

Brain atrophy may predict risk for early Alzheimer's disease

A study involving 159 older adults (average age 76) has confirmed that the amount of brain tissue in specific regions is a predictor of Alzheimer’s disease development.

Reviving a failing sense of smell through training

The olfactory bulb is in the oldest part of our brain. It connects directly to the

Why diabetes is linked to cognitive impairment in older adults

Why is diabetes associated with cognitive impairment and even dementia in older adults? New research pinpoints two molecules that trigger a cascade of events that end in poor blood flow and brain atrophy.

For the brain, iron levels may need to be just right

Iron deficiency is the world's single most common nutrient deficiency, and a well-known cause of impaired cognitive, language, and motor development. Many countries therefore routinely supplement infant foods with iron.

Pages