bed nuclei

a clump of gray matter surrounding the stria terminalis, deep within the brain, near the thalamus. It receives information from the prefrontal cortex and hippocampus and communicates with several lower brain regions that control stress responses and defensive behaviors.

Damage to amygdala can be compensated by another region

September, 2010

A memory function thought to require a specific brain region called the amygdala has now been found to be able to be performed by another region, if the amygdala is impaired.

A number of studies in recent years have revealed the amazing ability of the human brain to compensate for damage down to its part. In the latest of these, it’s been found that loss of the amygdala doesn’t have to mean that new memories will be void of emotion. Instead, it appears, a region called the bed nuclei can step in to take its place. The bed nuclei are slower to process information than the amygdala, and in normal circumstances are inhibited by the amygdala. The study looked specifically at fear conditioning, for which the amygdala has been considered crucial.

The finding offers the hope that therapies to promote compensatory shifts in function might help those who have suffered damage to parts of their brain.

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