Memory problems not the only predictor of later mild cognitive impairment

August, 2010

A study finds poor learning plus depression or slow processing speed predicts the development of amnestic mild cognitive impairment for seniors.

Amnestic mild cognitive impairment often leads to Alzheimer's disease, but what predicts aMCI? A study involving 94 older adults has revealed that lower performance on tests measuring learning, in conjunction with either slower visuomotor processing speed or depressive symptoms, predicted the development of aMCI a year later with an accuracy of 80-100%. It is worth emphasizing that poor learning alone was not predictive in that time-frame, although one learning measure was predictive of aMCI two years later. Interestingly, neither gender nor possession of the ‘Alzheimer’s gene’ —long believed to be risk factors for mild cognitive impairment — had any substantial influence on later impairment.


[1690] Han, D. S., Suzuki H., Jak A. J., Chang Y-L., Salmon D. P., & Bondi M. W.
(2010).  Hierarchical Cognitive and Psychosocial Predictors of Amnestic Mild Cognitive Impairment.
Journal of the International Neuropsychological Society. 16(04), 721 - 729.