Data from 1,425 cognitively healthy older adults (70-89) has found that a diagnosis of chronic obstructive pulmonary disease (COPD) was associated with an 83% greater risk of developing non-amnestic mild cognitive impairment. The greatest risk was among patients who had COPD for more than five years.
Over the study period, 230 (16%) developed amnestic MCI, 97 (7%) nonamnestic MCI, 27 (2%) MCI of unknown type, and 16 dementia (1%).
 . A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment. JAMA Neurology [Internet]. 2014 ;71(5):581 - 588. Available from: http://dx.doi.org/10.1001/jamaneurol.2014.94