Variations in eye structure and function seen early in Alzheimer's

More evidence for early changes in the eye in Alzheimer’s disease comes from a study involving both rats and postmortem human retinas. Changes were found in the retinal pigment epithelial layer (which harbors the supportive cells located in the back of the eye) and in the thickness of the choroidal layer that has blood vessels providing nutrients to the retina.

The finding is consistent with growing evidence that glaucoma is a neurodegenerative disorder similar to Alzheimer’s.

http://www.eurekalert.org/pub_releases/2014-03/cmc-vie031714.php

http://www.eurekalert.org/pub_releases/2013-11/gumc-cte110113.php

[3613] Tsai, Y., Lu B., Ljubimov A. V., Girman S., Ross-Cisneros F. N., Sadun A. A., et al.
(2014).  Ocular Changes in TgF344-AD Rat Model of Alzheimer's Disease.
Investigative Ophthalmology & Visual Science. 55(1), 523 - 534.

Related News

Data from 330 participants in The 90+ Study, of whom 70% were women, has revealed an overall annual incidence rate of 18.2% for dementia, rising from 12.7% per year in the 90-94 age group, to 21.2% in the 95-99 age group and 40.7% per year in the 100+ age group.

A study involving over 1000 older men and women (60-75) with type-2 diabetes has found that those with higher levels of the stress hormone cortisol in their blood are more likely to have experienced cognitive decline.

Following on from studies showing that a Mediterranean-like diet may be associated with a lower risk of Alzheimer's disease and may lengthen survival in people with Alzheimer's, a six-year study of 712 New Yorkers has revealed that those who were most closely following a Mediterranean-like diet

A new test has been developed that measures amyloid-beta oligomers in the cerebrospinal fluid, promising a reliable means of early diagnosis.

A computerized self test (CST) has been developed that is 96% accurate in diagnosing Alzheimer’s and

Both diabetes and clinical depression are known to be risk factors for dementia. Now a study that tracked nearly 4000 diabetics over 5 years has found having both increased the risk 2.7-fold.

A brain scanning study using Pittsburgh Compound B, involving 42 heal

Data from over 900 community-dwelling older adults participating in the Rush Memory and Aging Project has found that greater purpose in life was associated with a substantially reduced risk of developing Alzheimer's disease, as well as a reduced risk of mild cognitive impairment and a slower rat

An analysis technique using artificial neural networks has revealed that the most important factors for predicting whether amnestic mild cognitive impairment (

Data from 625 elderly Americans, followed for an average of 8.5 years, has revealed that those with very good or excellent vision at the beginning of the study had a 63% reduced risk of dementia over the study period.

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news
Error | About memory

Error

The website encountered an unexpected error. Please try again later.