includes the hippocampus, the amygdala, and the entorhinal and perirhinal cortices. Although given this name, the idea that this is an integrated memory system with a common function has recently been questioned. It is observed that the various components evolved at different points. Nevertheless, we may say that the MTL appears to be involved in declarative learning (facts and events), being particularly important during initial learning. There is some evidence that long-term consolidation of memories is guided by the MTL, in particular by the entorhinal cortex (which is damaged in the early stages of Alzheimer’s disease). Moreover, a recent study showed that progressive atrophy in the medial temporal lobe was the most significant predictor of cognitive decline in seniors.