Memory complaints linked to higher risk of MCI & dementia

Data from 6257 older adults (aged 55-90) evaluated from 2005-2012 has revealed that concerns about memory should be taken seriously, with subjective complaints associated with a doubled risk of developing mild cognitive impairment or dementia, and subjective complaints supported by a loved one being associated with a fourfold risk. Complaints by a loved one alone were also associated with a doubled risk. Among those with MCI, subjective complaints supported by a loved one were associated with a threefold risk of converting to dementia.

Of the 4414 initially cognitively normal, 14% developed MCI or dementia over the course of the study (around 5 years); of the 1843 with MCI, 41% progressed to dementia.

http://www.futurity.org/worry-about-memory-predicts-alzheimer%E2%80%99s-risk/

[3573] Gifford, K. A., Liu D., Lu Z., Tripodis Y., Cantwell N. G., Palmisano J., et al.
(2014).  The source of cognitive complaints predicts diagnostic conversion differentially among nondemented older adults.
Alzheimer's & Dementia. 10(3), 319 - 327.

Related News

A study involving 74 older adults (70+), of whom 3 had mild dementia, 33 were cognitively normal and 38 had mild cognitive impairment, has found that high levels of "good" cholesterol and low levels of "bad" cholesterol correlated with lower levels of the amyloid-beta plaques in the brain (a hal

Data from 11 different cohort studies, involving more than 600,000 people from around the world, has found that:

Data from AREDS2, involving 4,203 older adults with age-related macular degeneration, has found that daily dietary supplements of either omega-3 polyunsaturated fatty acids (also found in fish) or lutein and zeaxanthin (nutrients found in green leafy vegetables) were not associated with reduced

A small trial involving seven older adults with insomnia has found that when they consumed 8 ounces of tart cherry juice twice daily for two weeks, they were able to sleep more than an hour longer each night (averaging 84 minutes) compared to when they took the placebo, and their sleep tended to

A study in which 136 older couples (average age 63) filled out questionnaires measuring their overall marriage quality and their perceived support from their spouse, has found that calcification in the coronary arteries was highest when both partners in the relationship viewed each other as offe

Previous research has indicated that about a quarter of older adults who become mildly depressed will go on to become seriously depressed within a year or two.

Two studies help explain why kidney disease increases the risk of cardiovascular diseases such as high blood pressure and vascular calcification. The mediator seems to be a hormone called FGF23, which is sensitive to the level of phosphates in the body.

A study in which 157 healthy adult volunteers were asked to regulate their emotional reactions to unpleasant pictures, has found that those who showed greater brain activation when regulating their negative emotions also had higher blood levels of interleukin-6 (a marker for inflammation) and in

A finding that free radicals promote longevity in the roundworm challenges the theory that free radicals (oxidants) are damaging and cause aging.

A study involving 614 patients with type 2 diabetes (mean age 62) has found that longer duration of diabetes was associated with more brain volume loss, particularly in the gray matter.

Pages

Subscribe to Latest newsSubscribe to Latest newsSubscribe to Latest health newsSubscribe to Latest news