Amnestic mild cognitive impairment often leads to Alzheimer's disease, but what predicts aMCI? A study involving 94 older adults has revealed that lower performance on tests measuring learning, in conjunction with either slower visuomotor processing speed or depressive symptoms, predicted the development of aMCI a year later with an accuracy of 80-100%. It is worth emphasizing that poor learning alone was not predictive in that time-frame, although one learning measure was predictive of aMCI two years later. Interestingly, neither gender nor possession of the ‘Alzheimer’s gene’ —long believed to be risk factors for mild cognitive impairment — had any substantial influence on later impairment.
 . Hierarchical Cognitive and Psychosocial Predictors of Amnestic Mild Cognitive Impairment. Journal of the International Neuropsychological Society [Internet]. 2010 ;16(04):721 - 729. Available from: http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=7812581&fulltextType=BT&fileId=S1355617710000512