News reports of research into memory June 2004

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June 2004

'Imagination' helps older people remember to comply with medical advice

A new study suggests a way to help older people remember to take medications and follow other medical advice. Researchers found older adults (aged 60 to 81) who spent a few minutes picturing how they would test their blood sugar were 50% more likely to actually do these tests on a regular basis than those who used other memory techniques. Participants were assigned to one of three groups. One group spent one 3-minute session visualizing exactly what they would be doing and where they would be the next day when they were scheduled to test their blood sugar levels. Another group repeatedly recited aloud the instructions for testing their blood. The last group were asked to write a list of pros and cons for testing blood sugar. All participants were asked not to use timers, alarms or other devices. Over 3 weeks, the “imagination” group remembered 76% of the time to test their blood sugar at the right times of the day compared to an average of 46% in the other two groups. They were also far less likely to go an entire day without testing than those in the other two groups.
The study appeared in the June issue of Psychology and Aging. Full reference
http://www.eurekalert.org/pub_releases/2004-06/nioa-ho060104.php

Stress reactions no guarantee of authenticity

Physical stress reactions have often been taken as evidence for the authenticity of a memory. A recent study investigated people with “memories” of alien abductions (on the grounds that these are the memories least likely to be true) and found that those who believed they had been abducted by aliens responded physically to recall of that memory in the same way as to recall of other, true, stressful events. The finding suggests that a person’s reaction to a memory is no evidence for whether or not it truly happened.
The study was published in the July issue of Psychological Science. Full reference
http://www.eurekalert.org/pub_releases/2004-06/aps-ptw062104.php

Stress no aid to memory

Numerous studies have questioned the accuracy of recall of traumatic events, but the research is often dismissed as artificial and not intense enough to simulate real-life trauma. A new study has used real stress: 509 active duty military personnel enrolled in survival school training were deprived of food and sleep 48 hours and then interrogated. A day later, only 30% of those presented with a line-up could identify the right person, only 34% identified their interrogator from a photo-spread and 49% from single photos shown sequentially (putting the interrogator in the same clothing boosted correct identification to 66%). Thirty people even got the gender wrong. Those subjected to physical threats (half the participants) performed worse.
The report appeared in the May/June issue of the International Journal of Law and Psychiatry. Full reference
http://www.newscientist.com/news/news.jsp?id=ns99995089

http://www.eurekalert.org/pub_releases/2004-06/yu-emp060304.php

http://www.eurekalert.org/pub_releases/2004-06/ns-mfy060904.php

Being fluent in two languages may help keep the brain sharper for longer

A study of 104 people aged between 30 and 88 has found that those who were fluent in two languages rather than just one were sharper mentally. Those fluent in two languages responded faster on tasks assumed to place demands on working memory, compared to those who were fluent in just English, at all age groups. This is consistent with the theory that constant management of 2 competing languages enhances executive functions. Bilingual volunteers were also much less likely to suffer from the mental decline associated with old age. The finding is consistent with other research suggesting that mental activity helps in protecting older adults from mental decline. The participants were all middle class, and educated to degree level. Half of the volunteers came from Canada and spoke only English. The other half came from India and were fluent in both English and Tamil.
The report appeared in the June issue of Psychology and Aging. Full reference
http://news.bbc.co.uk/2/hi/health/3794479.stm

Learning a second language may not be as laborious as believed

A study of adult learners of a second language has revealed that their brains still possess a surprising facility for learning words — much greater than the learner is consciously aware of. College students learning first-year French demonstrated brain activity that was clearly discriminating between real and pseudo-French words after only 14 hours of classroom instruction, although the students performed only at chance levels when asked to consciously choose whether or not the stimuli were real French words. The greater the exposure to French, the larger the difference in brain response to words and pseudo words.
The report was published June 13 in the on-line edition of Nature Neuroscience. Full reference
http://www.eurekalert.org/pub_releases/2004-06/uow-baw061104.php

Some brains age more rapidly than others

Investigation of the patterns of gene expression in post-mortem brain tissue has revealed two groups of genes with significantly altered expression levels in the brains of older individuals. The most significantly affected were mostly those related to learning and memory. One of the most interesting, and potentially useful, findings, is that patterns of gene expression were quite similar in the brains of younger adults. Very old adults also showed similar patterns, although the similarity was less. But the greatest degree of individual variation occurred in those aged between 40 and 70. Some of these adults showed gene patterns that looked more like the young group, whereas others showed gene patterns that looked more like the old group. It appears that gene changes start around 40 in some people, but not in others. It also appears that those genes that are affected by age are unusually vulnerable to damage from agents such as free radicals and toxins in the environment, suggesting that lifestyle in young adults may play a part in deciding rate and degree of cognitive decline in later years.
The study appeared in the June 24 issue of Nature. Full reference
http://www.eurekalert.org/pub_releases/2004-06/chb-dgi060204.php

Estrogen-alone hormone therapy could increase risk of dementia in older women

A new report from the Women's Health Initiative Memory Study suggests that older women using estrogen-alone hormone therapy could be at a slightly greater risk of developing dementia, including Alzheimer's disease (AD), than women who do not use any menopausal hormone therapy. Among 10,000 women using conjugated equine estrogens, 37 could be expected to develop dementia, compared to 25 in 10,000 women using the placebo. Previous reports from the Study found a greater risk with hormone therapy involving both estrogen plus progestin: among 10,000 women over age 65 using estrogen plus progestin there might be 45 cases of dementia compared to 22 cases in 10,000 older women on placebo.
It was also reported that beginning estrogen-alone hormone therapy after age 65 can have a small negative effect on overall cognitive abilities and that this negative effect may be greater in women with existing cognitive problems.
These findings appeared in the June 23/30 issue of the Journal of the American Medical Association. Full reference 2
http://www.eurekalert.org/pub_releases/2004-06/nioa-eht062204.php

http://www.eurekalert.org/pub_releases/2004-06/wfub-etd061704.php

Estrogen boosts memory in men with prostate cancer

A new study suggests that high doses of estrogen may improve long-term memory and decrease feelings of confusion in men whose testosterone levels have been lowered to treat advanced prostate cancer. The findings suggest that hormone deprivation, prostate cancer or a combination of the two significantly impair verbal memory, while estrogen therapy significantly improves verbal memory performance. Hormone deprivation appears to slow working memory performance, but did not affect accuracy. Supplementation with estrogen did not affect working memory.
The paper was presented on June 6 at the American Society for Clinical Oncology annual meeting in New Orleans, La. Reference
http://www.eurekalert.org/pub_releases/2004-06/ohs-ebm060604.php

Cognitive dysfunction found in women with breast cancer prior to treatment

The first study to evaluate cognitive skills prior to chemotherapy has found significant deficits in neuropsychological function in breast cancer patients before undergoing chemotherapy, and suggests the incidence of "chemobrain," a widely reported side effect in women undergoing treatment for breast cancer, may be overestimated. The study found 35% of the women demonstrated baseline cognitive impairment with significant deficits in verbal learning and memory prior to chemotherapy. Psychomotor processing speed and attention, non-verbal memory, naming, complex visual tasks and hand fine motor dexterity also trended toward significant impairment compared to the controls.
The study was published in the June 21 issue of CANCER.
http://www.eurekalert.org/pub_releases/2004-06/jws-scw061604.php
Full reference
The full study is available via Wiley InterScience (http://www.interscience.wiley.com/cancer-newsroom).

Brain development and puberty may be key factors in learning disorders

New research suggests that the brains of children with learning problems not only appear to develop more slowly than those of their unaffected counterparts but also actually may stop developing around the time of puberty's onset. In the study, children with impairments started out about three years behind, but their rate of improvement was very similar to that of the children without impairments — until around 10 years, when further development in the children with learning problems stopped. The researchers suggest that delayed brain development and its interaction with puberty may be key factors contributing to language-based learning disabilities such as dyslexia. This hypothesis suggests a completely new approach to the study of learning problems. It also points to the importance of early intervention.
The article appeared in the June 29 issue of the Proceedings of the National Academy of Sciences. Full reference
http://www.eurekalert.org/pub_releases/2004-06/nu-bda061604.php

We weren't made to multitask

A new imaging study supports the view that we can’t perform two tasks at once, rather, the tasks must wait their turn — queuing up for their turn at processing.
The study was published in the June issue of Psychological Science. Full reference
http://www.eurekalert.org/pub_releases/2004-06/aps-wwm060704.php

Alzheimer's may leave some forms of memory intact

A new study has demonstrated that people with Alzheimer's disease retain the capability for a specific form of memory used for rote learning of skills, despite their other memory loss. The finding suggests new strategies to improve training and rehabilitative programs for Alzheimer's sufferers. It also confirms other studies suggesting that a number of brain systems are more intact in Alzheimer's than previously thought.
The report was published in the June 10 issue of Neuron. Full reference
http://www.eurekalert.org/pub_releases/2004-06/hhmi-als060404.php
http://www.eurekalert.org/pub_releases/2004-06/cp-ssh060304.php

More support for social skill theory of brain evolution

Why do we have such large brains? Brains are very costly — they require a lot of energy. Gaining credence in recent years has been the idea that the advantage of our brain has been through the complex social skills it allows. Evidence supporting this has come from a study of records of primates deceiving each other for personal gain. The bigger the neocortex, it seems, the more likely a primate is to practice deception. The researchers gathered instances of deception across 18 species of primate and found no link with overall brain size, but a clear match between devious deeds and neocortex volume.
The study will be reported in the Proceedings of the Royal Society: Biological Sciences. Reference
http://www.guardian.co.uk/life/dispatch/story/0,12978,1250723,00.html

http://www.newscientist.com/news/news.jsp?id=ns99996090

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