Alzheimer's & Other Dementias

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People with MCI who later developed Alzheimer's disease showed 10-30% greater brain atrophy in two specific regions.

A three-year study involving 169 people with mild cognitive impairment has found that those who later developed Alzheimer's disease showed 10-30% greater atrophy in two specific locations within the

A study has found that mental fluctuations were very rare in those without Alzheimer's, but occurred in nearly 12% of those with very mild or mild Alzheimer’s.

A study involving 511 older adults (average age 78) has found that 11.6% of those with very mild or mild Alzheimer’s (43% of the participants) had mental lapses, compared to only 2 of the 295 without Alzheimer’s. Those with mental lapses also tended to have more severe Alzheimer’s.

Previous research suggesting loss of smell function may serve as an early marker of Alzheimer's disease has now been supported by evidence from genetically engineered mice.

Previous research suggesting loss of smell function may serve as an early marker of Alzheimer's disease has now been supported by a finding that in

A study using two training programs to help dementia patients regain eating skills, found spaced retrieval training was particularly effective.

Loss of memory and problems with judgment in dementia patients can cause difficulties in relation to eating and nutrition; these problems in turn can lead to poor quality of life, pressure ulcers and infections.

A clinical trial has found improvement in verbal (but not general) memory in patients with mild Alzheimer's who drank a nutritional cocktail for 12 weeks.

A European trial involving 225 patients with mild Alzheimer's has found that those who drank Souvenaid (a cocktail of uridine, choline and the omega-3 fatty acid DHA, plus B vitamins, phosopholipids and antioxidants) for 12 weeks were more likely to improve their performance in a delayed verbal

Healthy older adults reporting subjective cognitive impairment are dramatically more likely to progress to MCI or dementia, and decline significantly faster.

Subjective cognitive impairment (SCI), marked by situations such as when a person recognizes they can't remember a name like they used to or where they recently placed important objects the way they used to, is experienced by between one-quarter and one-half of the population over the age of 65.

Two large studies have found moderate exercise was associated with a lower risk of developing mild cognitive impairment. A small study suggests women may benefit more than men.

A German study involving nearly 4000 older adults (55+) has found that physical activity significantly reduced the risk of developing mild cognitive impairment over a two-year period.

A mouse study found Rapamycin improved learning and memory and reduced Alzheimer's-like damage in the brain.

Evidence that levels of damaged tau protein in the cerebrospinal fluid is associated with atrophy in the medial temporal lobe may help diagnose Alzheimer’s early.

A study involving 57 cognitively healthy older adults has found that those who showed decreased memory performance two years later (20 of the 57) had higher baseline levels of phosphorylated tau231 in the

A large five-year study concludes that late-life hypertension doubles the risk of dementia in those with executive dysfunction only (but not for those with memory dysfunction alone or memory and executive dysfunction).

Midlife hypertension has been confirmed as a risk factor for the development of dementia in late life, but there have been conflicting findings about the role of late-life hypertension.

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