catecho-O-methyltransferase gene

codes for the enzyme that metabolizes neurotransmitters like dopamine and norepinephrine, and comes in two common versions (met and val -- met contains the amino acid methionine at a point in its chemical sequence where val contains a valine). The COMT gene, like the BDNF gene, has been implicated in schizophrenia as well as cognitive function.

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